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"Prohibition will work great injury to the cause of temperance. It is a species of intemperance within itself, for it goes beyond the bounds of reason in that it attempts to control a man's appetite by legislation, and makes a crime out of things that are not crimes. A Prohibition law strikes a blow at the very principles upon which our government was founded."

Abraham Lincoln - Former U.S. President


Cannabis & Health

Medical uses of cannabis and scientific research

Medical uses and scientific research

The therapeutic effects of cannabinoids are most well established for THC, which is the primary psychoactive ingredient of marijuana. But it does not follow from this that smoking marijuana is good medicine.

Advances in cannabinoid science of the past 16 years have given rise to a wealth of new opportunities for the development of medically useful cannabinoid-based drugs. The accumulated data suggest a variety of indications as follow:

Pain relief, in patients with spinal cord injury, peripheral neuropathic pain, or central post stroke pain, patients with chronic pain and insomnia and postoperative pain patients.

Antiemetic, occurred under a variety of conditions, such as acute viral illness, cancer, radiation exposure, cancer chemotherapy, postoperative recovery, pregnancy, motion, and poisoning.

Appetite Stimulation in patient with anorexia, Alzheimer. THC shows to be useful in stimulating appetite and preventing weight loss in cancer and AIDS patients.

Anorexia Nervosa, the profile of cannabinoid drug effects suggests that they are promising for treating wasting syndrome in AIDS patients. Nausea, appetite loss, pain, and anxiety are all afflictions of wasting, and all can be mitigated by marijuana.

Neurological Disorders, muscle spasticity, particularly in multiple sclerosis patients and spinal cord injury victims; movement disorders, such as Parkinson's disease, Huntington's disease, Tourette's syndrome and epilepsy. Marijuana is not proposed as a cure for such disorders, but it might relieve some associated symptoms.

Acquired Immune Deficiency Syndrome (AIDS). Patients with cachexia, neuropathy, or any significant pain problem.

Chemotherapy Patients, especially those being treated for the mucositis, nausea, and anorexia.

Glaucoma. Marijuana and THC have been shown to reduce IOP (Intraocular Pressure) by an average of 24% in people with normal IOP who have visual-field changes.

Migraine Headaches, recent studies show available evidence from animal and human indicates that cannabinoids can have a substantial analgesic effect.

Also: Depression, Anxiety, Arthritis, Chronic fatigue, Cramps, Croh'n, Fever, Rheumatism, Neuralgia, Stress, Anemia, Insomnia.

References: Janet Joy. Assessing the Science Base by Institute of Medicine. Mohamed Ben Amar. Cannabinoids in Medicine, a review of their therapeutic potential.

Tardive Dyskinesia victims benfit from cannabis

So often the wonder drugs of modern medicine can have side effects that are way worse than the condition they were meant to treat. Information in this article relates to the condition tardive dyskinesia, a movement disorder caused by ingesting the medication Reglan. There are reports that cannabis can have a positive effect on the symptoms of this unfortunate man-made condition.

GENERIC NAME: metoclopramide

BRAND NAME: metoclopramide, Reglan, Reglan ODT, Metozol ODT, Octamide, (Maxolon discontinued)

Metoclopramide is used on a short term basis (4 to 12 weeks) for treating patients with heartburn and esophagitis due to GERD and for treating patients who have gastroparesis. Metoclopramide is used to promote emptying of the stomach prior to radiological examinations and to facilitate passage of tubes passed through the nose or mouth and into the small intestine. It is used for treating impaired function of muscles of the small intestine that may give rise to symptoms that mimic intestinal obstruction (nausea, vomiting, and abdominal distention). Metoclopramide also is used in the treatment of nausea due to surgery or cancer chemotherapy. 

Metoclopramide is a "prokinetic" drug that stimulates the muscles of the gastrointestinal tract including the muscles of the lower esophageal sphincter, stomach, and small intestine by interacting with receptors for acetylcholine and dopamine on gastrointestinal muscles and nerves. 

 In some patients, particularly those with diabetes, damage to nerves in the stomach can interfere with function of the muscles and cause delayed emptying of the stomach, resulting in nausea, vomiting, a sense of abdominal fullness and distention, and heartburn (diabetic gastroparesis). Metoclopramide is can be effective in relieving the symptoms related to diabetic gastroparesis by stimulating more rapid emptying of the stomach as well as decreasing the reflux of stomach acid into the esophagus. Dopamine receptors on nerves in the brain are important in producing nausea. Metoclopramide interacts with the dopamine receptors in the brain and can be effective in treating nausea. The FDA approved metoclopramide in June 1985.

The most serious neurological side effects of metoclopramide are symptoms mimicking Parkinson's disease, involuntary muscle movements, facial grimacing, and dystonic reactions resembling tetanus. Fortunately, these more serious side effects are infrequent and usually - though not always - disappear when metoclopramide is discontinued. Patients with Parkinson's disease can experience worsening of symptoms with metoclopramide. Metoclopramide may impair the mental and/or physical abilities to drive or operate machinery. 

The following testimonial provided by

Ben Leer
Benjamin Leer
National Awareness Coordinator
Tardive Dyskinesia Center

<This email address is being protected from spambots. You need JavaScript enabled to view it.>

Tardive Dyskinesia (TD) is a result of damage to the bodily systems that process dopamine, and is typically caused by exposure to certain neurological medications - including Reglan.

The symptoms of TD, which are irreversible and incurable, mimic those of Parkinson’s disease. Tardive Dyskinesia victims suffer from involuntary, repetitive movements which often continue after the drug is no longer used. some patients do report that their use of marijuana relieves their symptoms. We feature the most up-to-date information on TD, its causes and all known treatment options. Additionally, we distribute free support books and informational packets to our users.

The best treatment is prevention - be very careful with any suggestion of exposure to the drug Reglan or it's competitors;

"...right now we are in the midst of a public outreach, attempting to educate families on the dangers of Reglan. Some studies have shown cannabis to be useful in helping patients manage the symptoms of tardive dyskinesia."

Long term affects of regular cannabis use on the brain

Joints1The long-term effects of cannabis on the mind, the personality and the brain itself are a source of contention. Some doctors assert that repeated, long-term use of the drug can cause personality changes at best, actual brain damage at worst. However it should be stated that no definitive proof of this has been accepted by the medical establishment, with some (such as the British Medical Council) having stated that cannabis has no such long-term effects.

Something reported by long-term users, however, is a feeling of "mushiness" in the head through heavy and long-term use. There is the feeling that you are always slightly stoned, and further smoking is just "topping up" the effects that are always already there. This considered (or justified) by confirmed users to be perfectly harmless and even beneficial in some ways as it contributes to a general feeling of relaxation with life, sustained creativity (though this can lack focus) and an underlying happiness.

However, if things are not going well in your life, this could easily transmute into a feeling of helplessness and depression. Or, if things are mundane, lethargy and disinterest: the artificial euphoria induced by injesting active ingredients in cannabis may become the only thing you have to look forward to, and this is certainly the best way to become psychologically dependent on the drug. Certainly - it should go without saying - if you find (or suspect) that heavy cannabis use is impacting upon your job or personal relationships, you need to seriously consider taking a few months off.

Because of this "topping up", some of the other effects can become more-or-less permanent, though you find you get used to the more unpleasant ones such as paranoia, and can generally tune them out. However, short-term memory loss may well affect you frequently. Bear in mind though that these should disappear again if you take a break from smoking, and quite rapidly too.